Agenda

 

FRIDAY, JANUARY 10, 2020

SESSION 1 – DIAGNOSING AMYLOIDOSIS

8:30

Introduction 

  • Purpose of Masterclass
  • Current State of the Field
  • Impacts of Delayed Diagnosis

Vaishali Sanchorawala

8:45

When to suspect amyloidosis 

  • Symptoms and Suspicion
  • Red Flags

Lisa Mendelson

 

 

9:00

How to diagnose amyloidosis 

  • Diagnostic Tools
  • Diagnostic Algorithm

Anita D’Souza

 

SESSION 2 – MANAGEMENT OF AL AMYLOIDOSIS

9:15

Staging and Risk stratification in
AL amyloidosis 

 

 

Vaishali Sanchorawala

9:30

Current therapies in AL amyloidosis

  • Standard of care
  • Novel agents
  • Role of stem cell transplantation

Larry Anderson

10:00

Quality of life in AL amyloidosis 

 

Anita D’Souza

10:15

How to approach patients with advanced
AL amyloidosis 

Anita D’Souza

10:30

Discussion: Challenges of AL therapies
and
clinical trials 

All Faculty

Break (10:50-11:05)

 

 

SESSION 3 –MANAGEMENT OF ATTR AMYLOIDOSIS

11:05

Introduction 

  • Epidemiology of hATTR and ATTRwt
  • Importance of early diagnosis and symptom
    monitoring in hATTR (How early should you
    target treatment?)
  • Staging and Risk stratification

John Berk

11:15

Cardiac ATTR amyloidosis 

  • Advances in TTR protein stabilization and
    degradation of amyloid fibrils for
    ATTR amyloidosis

Mat Maurer

 

11:35

Neuro ATTR amyloidosis 

  • Neuropathy burden and management
  • Impact of gene silencers
  • Neuropathy scales for clinical practice and trials

Sami Khella

11:55

Use of PYP Scintigraphy 

Mat Maurer

12:05

Genetic Testing and Counseling 

John Berk

12:15

Discussion: Sequencing of TTR stabilizers and
silencers in the treatment of ATTR, new clinical
trials 

All

Lunch 12:35-1:25




SESSION 4 – BREAK OUT SESSIONS WITH HANDS ON TEACHING

1:25

Track 1

Track 2

Track 3

20 mins rotation

(+5 extra
minutes for
room changes)

Fat Pad
Aspiration

Lisa Mendelson

Reading PYP Scintigraphy

Mat Maurer

Specialty Pharmacy and Prior Authorizations

David Hughes

 

SESSION 5 – MULTIDISCIPLINARY APPROACH TO AMYLOIDOSIS

2:30 -2:50

  • Why multidisciplinary is important
  • BU model of care

Vaishali Sanchorawala

3:00

Discussion: Collaboration with
referral centers

All faculty

3:30

End